Granzyme B Monoclonal Antibody

Sizes: 100μL, 200μL

Catalogue Numbers: PA5024R-100, PA5024R-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Granzyme B

Target Synonym: C11, CCPI, CGL-1, CGL1, CSP-B, CSPB, CTLA1, CTSGL1, HLP, SECT, Granzyme B, GZMB

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human

Application: IHC-P

Clonality: Monoclonal

Clone No.: YN00905r

UNIProt ID: P10144

Background: Granzyme B is a serine protease, which mediates the apoptosis signaling pathway of cytotoxic T lymphocytes (CTL) and natural killer cells (NK). Granzyme B is synthesized in the form of inactive protease, stored in lysosomal granules and released during the degradation of effector cells. The results shows that granzyme B is expressed in peripheral T-cell lymphoma (PTCL) and NK cell lymphoma by immunohistochemistry. The expression of cytotoxic proteins may play an important role in the differentiation and classification of peripheral T-cell and NK cell lymphoma, such as granzyme B, because many tumors of this type do not have specific morphology and phenotype.

The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.

Shipping: Ice bag

Research Use Only