FV-100 is a potent, selective and orally active anti-varicella zoster virus agent. FV-100 is a prodrug of CF-1743. FV-100 exhibits very low toxicity in vivo.

Product information

CAS Number: 956483-03-7

Molecular Weight: 534.04

Formula: C27H36ClN3O6

Chemical Name: [(2R,3S,5R)-3-hydroxy-5-[2-oxo-6-(4-pentylphenyl)-2H,3H-furo[2,3-d]pyrimidin-3-yl]oxolan-2-yl]methyl (2S)-2-amino-3-methylbutanoate hydrochloride

Smiles: Cl.CC(C)[C@H](N)C(=O)OC[C@H]1O[C@H](C[C@@H]1O)N1C=C2C=C(OC2=NC1=O)C1=CC=C(CCCCC)C=C1

InChiKey: CAHTYTZOAVUCIU-ZMQZINMSSA-N

InChi: InChI=1S/C27H35N3O6.ClH/c1-4-5-6-7-17-8-10-18(11-9-17)21-12-19-14-30(27(33)29-25(19)36-21)23-13-20(31)22(35-23)15-34-26(32)24(28)16(2)3;/h8-12,14,16,20,22-24,31H,4-7,13,15,28H2,1-3H3;1H/t20-,22+,23+,24-;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

FV-100 is intensely fluorescent when illuminated by wavelengths of 340-380 nm. FV-100 (1 h) produces a different distribution in HeLa cells.

In Vivo:

FV-100 (50-500 mg/kg; p.o.) does not induce biologically relevant respiratory changes or any apparent neuropharmacological effects in rats.

Products are for research use only. Not for human use.