JNK3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA26563-50, RA26563-100

Citations, Manuals and MSDS Available upon request.

Background: mitogen-activated protein kinase 10 (MAPK10) Homo sapiens The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-300

Alternative Names: Mitogen-activated protein kinase 10 (MAP kinase 10;MAPK 10;EC 2.7.11.24;MAP kinase p49 3F12;Stress-activated protein kinase 1b;SAPK1b;Stress-activated protein kinase JNK3;c-Jun N-terminal kinase 3)

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 5602

Protein MW (KDa): 54

SWISS: P53779

Source: Rabbit

Research Use Only