LGR6 Polyclonal Antibody

Catalogue Numbers: BS62105-50, BS62105-100

Sizes: 50µl, 100µl

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

Swiss-Prot: Q9HBX8

Host: Rabbit

Reactivity: Human, Rat

Applications: WB

All Applications: WB: 1:500~1:1000

Background: G protein-coupled receptors (GPCRs),also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interact with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling and are involved in many pathological conditions. The GPCR family represents the largest class of targets for modern drugs. Leucine-rich repeat-containing G protein-coupled receptor 6 (LGR6) is an orphan-A GPCR with an N-terminal ectodomain comprising variable leucine-rich repeats, a 7TM region and a unique C-terminal intracellular tail.The sequence of LGR6 is similar to TSHR, FSHR and LHR. LGR6 is predominantly expres-sed in the adrenal gland, ovary and uterus.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: LGR6 polyclonal antibody detects endogenous levels of LGR6 protein.

Extra Notes: Western blot (WB) analysis of LGR6 polyclonal antibody at 1:500 dilution
Lane1:HCT116 whole cell lysate(40ug)
Lane2:MCF-7 whole cell lysate(40ug)
Lane3:Hela whole cell lysate(40ug)
Lane4:PC12 whole cell lysate(40ug)

Bioworld Molecular Weight: ~ 110kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: Aldehyde oxidase;Aldehyde oxidase 1;Azaheterocycle hydroxylase;AOX1;AO

Immunogen: Synthetic peptide, corresponding to Human LGR6 .

Conjugate: Unconjugated

Modification: Unmodified